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We Operate Under Good Laboratory Practices

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Residue Studies

Battelle can help you move your product to market quickly with GLP-compliant coordinated, customized residue studies designed to meet your regulatory compliance and global product registration needs. We offer comprehensive residue study design, management and execution, from single studies to full programs and study directorship with all studies designed to meet current European and U.S. regulations (Regulation (EC) No. 1107/2009, add FIFRA-EPA GLP).


Our residue analysis experts evaluate the safety, distribution, and metabolism of pesticides and other chemicals in soils and plant tissue, identifying potential concerns. 

Looking for fast, reliable results for regulatory compliance?
Contact us today to learn more.
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We have a proven track record of agrochemical analytical experience and residue study expertise in the U.S. and Europe. Our highly experienced staff operates under Good Laboratory Practices to fully meet international regulatory guidelines and help you move your product to market.  We can coordinate the entire residue process and develop, adapt, and validate new methodologies quickly and reliably. Our team of experts can serve as your study director or principle investigator for a range of studies.


Our services include:

Residue Analysis and Reporting
We have extensive analytical expertise with more than 70 different active ingredients and metabolites covering all major classes of pesticides, herbicides, fungicides and biopesticides, which we can analyze in crops, soil, water, air, animal tissue and body fluids. We have the state-of-the-art facilities and technical expertise to perform highly sensitive reproducible residue analyses and adapt, develop and validate new methods as they are needed. Analytical capabilities include LC-MS/MS, UPLC, HPLC with UV, fluorescence, electrochemical and diode-ray detection, high resolution accurate mass (orbitrap), GC with FID, FPD, ECD and MSD.

Field Trial Management
Battelle can manage your entire field trial process, from sourcing field contractors to sample transit and tracking, sample preparation, customized reporting and product registration support. We will plan and manage your field trials to meet international regulatory guidelines and ensure that your study meets your deadlines and requirements.

Ecotox/Analytical Support
We have more than 10 years of experience performing analytical phases in support of ecotox studies in conjunction with "live phase" partners. Analyzing pesticide and pharmaceutical active ingredients, our state of the art facilities are equipped with LC-MS/MS and HPLC systems suitable to determine the low levels of analytes from ecotox studies to derive endpoints.

Identification of Unknown Molecules
Battelle experts can identify unknowns and provide evidence-based suggestions on structures using an array of instrumentation (QExactive -accurate mass, LC-MS/MS QTRAP).

Method Development/Validation/Independent Laboratory Validation
Our study directors and analysts have extensive experience developing and validating robust methods for a variety of complex matrices (crops, soil, water, air, animal tissue and body fluids) to satisfy EU and US analytical method guidelines including:
  • Thermo QExactive accurate mass
  • SANCO/825/00 Rev 8.1
  • OCSPP (OPPTS) 860 series guidelines
As well as validating standard multi-residue procedures for post-registration monitoring (QuEChERS, DFG S19 etc.), Battelle’s experienced analysts can develop and validate compound-specific methods for pre-registration studies on a wide variety of matrices.   

Our equipment consists of:
  • Sciex 6500,5500 and 5000 LC-MS/MS systems
  • Agilent HPLC and UHPLC systems
  • Agilent GC/MS systems
  • Thermo QExactive accurate mass

In addition, we are experienced in performing the Independent Laboratory Validation to prove robustness of the primary method. 


Move your products to market quickly and confidently with coordinated, customized residue studies designed for reliable regulatory compliance and global product registrations. Battelle can coordinate the entire residue program, determine the relevant residue definition, and harmonize the Good Agricultural Practice. Battelle has extensive analytical experience adapting, developing and validating new methods quickly and reliably.


Rapid Screening for Agrichemical Residues


Pesticides and other agrichemicals have been found in the source water supplies in many part of the United States. Many of these chemicals have been shown to persist in the finished drinking water. Agrichemical developers and manufacturers need accurate, objective answers to determine the persistence of the chemicals they are working with, and the most effective methods to keep drinking supplies safe.


Battelle developed a new testing methodology to rapidly screen water samples for a number of emerging contaminants and current-use pesticides. We then studied different treatment strategies to determine the most effective way to remediate and dispose of compromised water. In order to compare different remediation options, we measured the attenuation of relatively high concentrations (low mg/L) of selected emerging contaminants and current-use pesticides with three separate advanced oxidation processes (AOPs):

  • Ozone-H2O2 Advanced Oxidation
  • Boron-Doped Diamond Electrode
  • UV-H2O2 Advanced Oxidation


In most cases, concentrations of target compounds were reduced by at least one order of magnitude within one hour. Rapid screening and remediation saves time and reduces the costs associated with keeping drinking supplies safe.

Office Locations

505 King Avenue
Columbus, OH 43201
Phone: 800-201-2011
or 614-424-6424


141 Longwater Drive, Suite 202
Norwell, MA 02061


Battelle UK Limited
29, Springfield Lyons Approach
Chelmsford Business Park
Springfield, Chelsmford
Essex, CM2 5LB, UK

Battelle UK Limited
Langston Technology Park
Langston Road
Hampshire, PO9 1SA, UK