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Accurate, Reliable Results We're helping to design better drugs and establish the safety of drugs under development.

Safety Pharmacology

Battelle applies more than 30 years of experience in premier safety pharmacology services to provide and develop in-depth scientific expertise, standardized protocols with known delivery timelines, and close communication with our clients to accelerate the drug development process. We customize drug discovery programs to meet each client’s specific needs. And our world-class facilities, combined with highly qualified, interdisciplinary teams, provide accurate and reliable results for every study.


Safety pharmacology is the science in which experimental models are created and used to detect the potential adverse or toxic effects of medications in the treatment of disease. Battelle works closely with pharmaceutical and biotechnology companies to design better drugs and to establish the safety of drugs under development.

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Battelle continuously reinvests in scientific research to offer our clients the opportunity to collaborate and advance development initiatives with an independent world leader in scientific research and development.

Highly Qualified Research Teams

  • Safety Pharmacology group of three Ph.D.-level physiologists/study directors, one master-level/DABT certified study director, four bachelor-level study coordinators, one bachelor-level engineer, and five American Association for Laboratory Animal Science (AALAS) accredited technicians

  • Full veterinary staff and surgical support

  • American Board of Toxicology and American Board of Veterinary Toxicology Diplomats

  • In-house quality-assurance unit

  • On-site histopathology and clinical pathology laboratories

  • Compliance with federal and industry regulations (ICH, OECD, EPA, FDA, DEA, USDA, OLAW, GLP)

State-of-the Art Technology
Battelle’s teams use world-class facilities and leading-edge equipment and technologies. We utilize state-of-the-art telemetry data acquisition and ECG analysis systems, as well as other assets to provide comprehensive nonclinical safety testing in a wide range of large and small models for analyses of a variety of test articles given by various routes of administration.

World-Class Facilities

  • USDA and National Institutes of Health (NIH) approved, American Association for Laboratory Animal Care (AALAC) accredited, FDA inspected

  • More than 350,000 square feet of lab/vivarium space

  • 15 rooms dedicated to telemetry

  • Approximately 85,000 square feet of support space including pathology, surgery and archiving

  • Access to 137Cs total-body gamma irradiator facility

  • Biosafety Level -2 and 3 laboratories


Expert ECG Analysis and Interpretation 

  • All ECGs are analyzed by the latest in ECG analysis software 

  • All intervals are QC’d by two trained technical personnel 

  • ECG waveforms are interpreted for rhythm and morphology by a board certified veterinarian cardiologist 

GLP-Compliant Core Battery Tests 

  • Cardiovascular with or without left ventricular pressure 

  • Pulmonary function evaluation in anesthetized and unanesthetized large and small models 

  • Central nervous system (FOBs, Tier II and Tier III tests)

  • Combination (CV/pulmonary/CNS) studies 

Other Services Available  

  • Exercise stress models

  • Echocardiographic evaluations 

  • Acute anesthetized and instrumented long-term models available for circumstances when ambulatory methods such as telemetry are not applicable

  • Imaging 

In addition to these core services, Battelle offers support services including genomics, proteomics, bioinformatics, chemistry, biomarkers and others to further advance the quality of our results. 


When you come to Battelle, you’ll find world-class expertise and dedicated, state-of-the-art facilities with everything you need to complete your study, from initial study design to regulatory support. And if your study requires an approach beyond the ordinary, don’t worry. At Battelle, we don’t just collect data – we solve problems.