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BATTELLE

Peripheral Pressure

Is peripheral pressure really the gold standard for measuring heart impact? While most toxicological studies use only peripheral pressures to determine CV effects, the question remains: could sites (central or peripheral) of recording pressures generate incorrect impressions on the safety and/or efficacy of test articles?

Measuring Pressures from Peripheral and Central Sites? 

A new Battelle poster, titled “Identification of Pharmacological Effects of Test Articles from Analysis of the Central and Peripheral Arterial Pressure Curves,” explores this important question.

We presented it for the first time at the 2017 Safety Pharmacology Society Annual Meeting in Berlin, and we’re excited to share it with the larger safety pharmacology community.

Sign up to receive the poster and learn:

Pressure Measurements

How pressure measurements can differ depending on collection site (central or peripheral)

Systolic and Pulse Pressures

How systolic and pulse pressures recorded from the peripherae are variably and significantly higher as compared to recording centrally

Magnitude Changes

How changes in magnitudes and time-courses of pressure may be multifactorial and complicated

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Presented at Safety Pharmacology Society Annual Meeting 2017

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