ThreatSEQ™ DNA Screening Web Service
Faster, Better Decisions for the Gene Synthesis Industry
ThreatSEQ DNA screening web service offers gene synthesis companies a faster alternative to manual and subjective DNA screening options. Now, these institutions are empowered to make better decisions for protecting themselves, their customers and society from potential biosecurity, compliance and liability risks–all while keeping costs manageable.
How It Works
Our technology is based on threat identification algorithms built around Battelle’s proprietary sequence of concern database containing more than 10,000 curated sequences and peer-reviewed microbial pathogenesis information. Because the database is organized around specific sequences rather than matching against the full genomes of known pathogens, the algorithms can identify the specific sequence in question and provide reviewers with actionable information to easily understand the threat level of a sequence and context for how to handle any customer follow up.
Features | Battelle | Current Practice |
High-Security | Yes | Yes |
Company-Specific | Yes | Yes |
Virulence Factor Focused | Yes | No |
Linked Metadata | Yes | No |
Continuous Updating | Yes | No |
Standardized and Objective Threat Status Score | Yes | No |
Complex Pattern Identification | Yes | No |
Comprehensive Reporting and Interpreting | Yes | No |
High Accuracy | Yes | No |
Web-Deployed | Yes | No |
Focused Input | Yes | No |
ThreatSEQ Database
The database was built on more than a decade of research into the factors that make pathogens dangerous. It compiles more than 10,000 sequences of concern comprising 100% of bacterial human/zoonotic agents and > 70% of human/zoonotic agents.
Threat Identification Algorithm
The algorithm rapidly scans a requested DNA sequence and looks for matches within the threat factors database. Matches may be entire gene sequences or parts of gene sequences. Our algorithm also provides information about the types of threats that a gene sequence may present by analyzing the structures of the genes and their resulting functions.
Featured Experts
-
Craig Bartling, Ph.D.
Data ScientistCraig’s background is in biochemistry, but his scientific expertise spans many areas, such as genomics, proteomics and protein characterization, and molecular biology. He is a recognized leader in biological data curation, with particular emphasis in data pertaining to biological threats and genetic engineering.
Related Solutions
-
solution
Biosecurity and Pandemic Preparedness
Our Biomedical Research Center conducts secure, state-of-the-art research, development, testing, and evaluation to enable proactive biosecurity preparedness critical to our national security, economic strength, and the well-being of people. -
solution
Precision Public Health
Battelle delivers the right intervention, to the right population, at the right time. Our interdisciplinary team of public health experts, data scientists and molecular geneticists improve health outcomes while promoting health equity. -
solution
Therapeutics, Prophylaxis and Diagnostics
Battelle operates the world’s largest non-governmental containment laboratories that help clients deliver life-saving diagnostic and therapeutic solutions for victims of chemical and biological warfare or pandemic diseases. -
solution
Chemical Agent Countermeasures
Battelle is a global leader in understanding the impact of chemical agents on our national security. Our experts execute the most thorough testing procedures and processes available under stringent quality management systems, providing guiding insights for the most important decisions.