IND-enabling Toxicology & Pharmacology

Key applications include:

Safety Pharmacology
Get the accurate, reliable results you need for FDA approval. Battelle applies in-depth scientific expertise, standardized protocols with known delivery timelines, and close communication with clients to accelerate the drug development process. Learn more.

Environmental Toxicology
Get clear, defensible data for product registration, environmental impact studies or remediation efforts. We provide environmental toxicology studies for agrochemicals, chemical and biological warfare agents, and chemicals used by the oil & gas and manufacturing industries.

Occupational Exposure
Understand the health and safety impact of chemicals used in industrial processes. Battelle’s toxicology studies provide clear answers for manufacturers and regulatory agencies.

We conduct routine and non-traditional toxicology studies, and can design or customize a study to meet your unique needs. Our toxicology team brings together world-class analysts, bioanalysts and statisticians with board-certified pathologists, toxicologists and ecotoxicologists for an integrated approach to toxicology. 

The Battelle Life Sciences Research Center has state-of-the-art facilities for all of your toxicology needs. With multiple locations in the Columbus, Ohio area, and Aberdeen, Maryland, our facilities feature:

• More than 400,000 square feet of dedicated in vitro and in vivo lab space suitable for a wide range of studies
• Facilities for all common laboratory species, small and large
• A highly controlled, GLP-compliant facility
• High-throughput testing capabilities
• Automated and semi-automated systems for data acquisition and control available for studies needing a high degree of precision
• Biosafety Level (BSL) 2 and BSL-3 high-containment testing facilities for highly infectious pathogens and high-hazard chemical agents
• In-house pathology and analytical and bioanalytical chemistry staff and laboratories for end-to-end service, including pharmacokinetic and pharmacodynamics studies

General Toxicology
We conduct exposure studies (including oral, dermal, subdermal, intravenous, subcutaneous, intramuscular and inhalation) for small molecules and biologics as well as complex mixtures, radiolabeled compounds, HHS and USDA select agents and toxins, and environmental contaminants. Learn more.

Inhalation Toxicology
Our capabilities include both nose/head-only and whole-body exposure inhalation studies for pharmaceuticals, agrochemicals, industrial chemicals and biological and chemical warfare agents. Learn more.

Developmental and Reproductive Toxicology (DART)
We offer a full battery of tests including fertility, developmental toxicity (teratology), juvenile studies and multigenerational reproductive studies. Learn more. 


Neurotoxicology
We offer a complete package of central nervous system (CNS) testing, including Tier I (Functional Observational Battery), Tier II (behavioral testing) and Tier III (EEG monitoring and neurohistopathological analysis). Learn more.

Cardiovascular and Pulmonary Toxicology
Our services include state-of-the-art telemetry, anesthetized preparations, and isolated (ex vivo) heart assays. Learn more.

At Battelle, we don’t just conduct studies – we solve problems. As the world's largest independent, non-profit research and development organization, we can bring in the right science and engineering talent to help you develop and validate new methods, design novel delivery mechanisms, and troubleshoot your most difficult study challenges. Get it done right the first time at Battelle.